Cytokeratin expression patterns in low-grade papillary urothelial neoplasms of the urinary bladder

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Immunohistochemical Differentiation between Urothelial Papillomas and Papillary Neoplasms of Low Malignant Potential of the Urinary Bladder.

BACKGROUND Urothelial papilloma and non-invasive papillary carcinoma are common neoplasms of the urinary bladder. Distinguishing papillomas and papillary carcinomas, especially the low grade type, is often debatable on the basis of histological features alone. MATERIALS AND METHODS We investigated immunohistochemical expression of cytokeratin 20 (CK20), p53, and Ki-67 in a group of 20 urothel...

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Concurrent malakoplakia and papillary urothelial carcinoma of the urinary bladder.

A case of malakoplakia and papillary urothelial carcinoma of the urinary bladder is reported. In this case, malakoplakia was an incidental finding in a biopsy of the urinary bladder of a 74-yr old female, who presented with hematuria. The biopsy showed a low-grade papillary urothelial carcinoma in close association with malakoplakia. This is a rare association of these lesions.

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Papillary Neoplasms of the Bronchus of Low-grade Malignancy.

In this paper we describe eight examples of papillary neoplasms of the bronchus in which atypical cytological features were present. In seven the lesion was localized and invasion was not present, in one extensive spread within the bronchial tree of a lobe had occurred but invasion into the lung parenchyma was doubtful. Lesions of this type receive little comment in the literature although they...

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IMP3 expression in urothelial carcinomas of the urinary bladder.

OBJECTIVE Superficial tumors including Ta, Tis, and T1 make up 75% of urothelial carcinomas of the bladder. While the behavior of these superficial urothelial cancers is relatively benign, invasive tumors have a significant mortality rate. However, Ta and T1 tumors might display different biological behavior. There is therefore a great need for biomarkers that can accurately distinguish the beh...

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Urothelial eddies in papillary urothelial neoplasms: a distinct morphologic pattern with low risk for progression.

We encountered an undescribed histologic feature of papillary urothelial neoplasms: "urothelial eddy", which was histologically reminiscent of squamous eddy of irritated follicular keratosis of the skin. A review of 756 patients with transurethral resection of bladder tumor revealed 10 patients (1.3%) of papillary urothelial neoplasms with urothelial eddies. All cases were male with a median ag...

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ژورنال

عنوان ژورنال: Cancer

سال: 2003

ISSN: 0008-543X,1097-0142

DOI: 10.1002/cncr.11265